At the Fourth Eurosymposium on Healthy Ageing,which was held in Brussels last November,Elena and I met Dr.Kris Verburgh,a medical doctor who is especially interested in biogerontology and the potential of this field of study to turn medicine on its head.Dr.Verburgh is only about 33 years old and has already…

Today,we conclude our two-part interview with Dr.Michael Fossel,you can find part one here.Changing tack a bit here,你在书中有点谈论人类程序性死亡;we're basically programmed to die through evolution's weird workings and you kind of flesh out what Josh Mitteldorf calls the demographic theory…

For the June edition of Journal Club,we will be taking a look at the recent paper entitled"老年肝脏前驱因子foxa2核层改变结合的变化”.We summarized the research in an article earlier this month.Summary Increasing evidence suggests that regulation of heterochromatin at the nuclear envelope underlies…

Researchers at the University of Virginia School of Medicine have discovered that as we age,our cells' nuclear membranes become misshapen,这会阻止我们的基因正常工作。Nuclear membranes become distorted with age The DNA in all our cells is the same;however,我们体内的细胞有很大的变异…

Today we bring you an interview with author and researcher Dr.Josh Mitteldorf who runs the aging research blog Aging Matters.Dr.乔什·密特多夫是一位进化生物学家,长期致力于老化科学领域的发展。His work in this field has focused on theories of aging.He asks the basic question:…

即将结束的老龄化会议,a joint effort between the SENS Research Foundation and Michael Greve's Forever Healthy Foundation,took place on March 15-17 in Berlin,gathering many aging researchers,advocates,investors,and other important members of the longevity community in one place.As we invited one of the best Russian journalists at educating the public…

In a new study,researchers at the Johns Hopkins Kimmel Cancer Center have shown that the epigenetic alterations associated with cancer evolve in an erratic manner during the early stages of tumor formation [1].These tumor-associated epigenetic changes ultimately focus on a subset of genes that are also observed in aging.癌症和衰老细胞…

Researchers have found that by manipulating a single RNA molecule,它们可以逆转细胞老化的某些方面并再生老化的细胞。Old cells resist regeneration As we grow older,our cells gradually age,leading to the development of various diseases.Therefore,inducing cellular regeneration is one of the approaches that researchers are using to…

Researchers at Duke University have managed to create functional human muscle tissue using skin cells as the starting point[1].This research builds on their previous work from 2015,当他们使用从肌肉活检中获得的细胞培养出第一个有功能的肌肉组织时[2]。Being able to create muscle cells using non-muscle tissue opens the door for…

The reprogramming of cells is a well-established technique in medicine and has been for over a decade now.It allows the en masse creation of patient-matched cells and is the basis for multiple current therapies.Cellular Senescence and Cellular Reprogramming share mechanisms Induced pluripotent stem cells (also known as iPS cells or iPSCs) can be…

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